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Congresso Brasileiro de Microbiologia 2023
 		Resumo: 630-1

630-1

IMPACT OF SARS-COV-2 INFECTION ON INTENSIVE CARE UNIT HOSPITALIZATION TIME IN COVID-19 PATIENTS

Autores:
Roberta Ferreira Ventura Mendes (UFES - Universidade Federal do Espírito Santo, PPG-RENORBIO - PROGRAMA DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA DA REDE NORDESTE) ; Priscila Marinho de Abreu (PPGBIOTEC - PROGRAMA DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA , UFES - Universidade Federal do Espírito Santo) ; Brena Ramos Athaydes (PPGBIOTEC - PROGRAMA DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA , UFES - Universidade Federal do Espírito Santo) ; Mariane Vedovatti Monfardini Sagrillo (PPGDI - PROGRAMA DE PÓS-GRADUAÇÃO EM DOENÇAS INFECCIOSAS, UFES - Universidade Federal do Espírito Santo) ; Rahyza Inácio Freire de Assis (PPGCO - PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS ODONTOLÓGICAS, UFES - Universidade Federal do Espírito Santo) ; Frederico Firme Figueira (UFES - Universidade Federal do Espírito Santo) ; Juliana Couto Vieira Carvalho (UFES - Universidade Federal do Espírito Santo) ; Liliana Cruz Spano (PPGDI - PROGRAMA DE PÓS-GRADUAÇÃO EM DOENÇAS INFECCIOSAS, UFES - Universidade Federal do Espírito Santo) ; Sandra Ventorin Von Zeidler (UFES - Universidade Federal do Espírito Santo, PPG-RENORBIO - PROGRAMA DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA DA REDE NORDESTE, PPGBIOTEC - PROGRAMA DE PÓS-GRADUAÇÃO EM BIOTECNOLOGIA , PPGCO - PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS ODONTOLÓGICAS)

Resumo:
Coronavirus disease 2019 (COVID-19) was first identified in December 2019 in Wuhan, China. Since then, it has rapidly spread worldwide, resulting in a global pandemic in 2020. While most patients with COVID-19 experience mild illness, around 30% of infected individuals may require hospitalization and specialized medical care, including admission to intensive care units (ICUs). Several factors may contribute to hospitalization time in the ICU in patients with COVID-19. This study aimed to analyze relationship between hospitalization time in the ICU, sex and age and the viral load on the clinical outcome of patients infected with SARS-CoV-2 in a reference hospital in the metropolitan region of Vitória, Espírito Santo. Forty-six patients admitted to the ICU between September 2020 and March 2021 were included in the analysis. All patients tested positive for SARS-CoV-2 via naso/oropharyngeal swab collection on admission, and a second swab was taken at the clinical outcome (hospital discharge or death). Demographic and clinical data were obtained from medical records with the patients' informed consent. Detection of SARS-CoV-2 was performed using the reverse transcription and amplification by real-time polymerase chain reaction (RT-PCR) technique. The study revealed that females had a longer hospitalization time in the ICU compared to males (Mann-Whitney test, p=0.024). However, the age group of the patients did not significantly influence the hospitalization time. Interestingly, most patients with positive PCR results for SARS-CoV-2 in clinical outcome samples had shorter hospitalization time (0 to 14 days) compared to patients with negative PCR results, who remained hospitalized for over 28 days (Chi-square test, p=0.001). However, when evaluating only the patients with positive samples in the outcome, the viral load did not significantly influence their hospitalization time. In conclusion, this study suggests that the main factor influencing hospitalization time of patients may be the comorbidities they present after being treated for the disease. Notably, most patients with longer hospitalization time did not show SARS-CoV-2 infection in the clinical outcome. Financial support: CAPES.

Palavras-chave:
 SARS-CoV-2, COVID-19, hospitalization time, ICU


Agência de fomento:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – CAPES